A-T Children’s Project Research Grant Program and Awards

The A-T Children’s Project supports promising research with sound scientific rationale. No idea is too novel for us to consider, as long as it has clear relevance for people with ataxia telangiectasia (A-T) and the potential to lead to a therapy. We are open to creative ideas conceived by investigators. From time to time, we also encourage projects that address a specific gap in scientific understanding, patient need or therapeutic development. In addition, we sometimes provide add-on, supplemental funding if a grant we already awarded shows significant progress and continued potential.

While the A-T Children’s Project has previously granted millions of dollars to support projects aimed at elucidating A-T biology, we are now focusing our limited funds on experiments whose success will provide a clear path to a treatment or intervention for A-T. For example, we are enthusiastic about exploring new DNA-based modalities that may cause a working ATM protein to be produced in the cerebella of people with A-T, or testing compounds that have a strong mechanistic hypothesis for having efficacy in a patient with A-T. We are also eager to support the development of biomarkers and digital tools that could improve and accelerate clinical development for A-T.